Sildenafil is an organic chemical compound that is used to treat erectile dysfunction and primary pulmonary hypertension. Sildenafil is an ingredient in a drug of the same name to help stimulate blood flow. This mechanism restores the erectile dysfunctional mechanism in a situation of sexual stimulation.
The active substance sildenafil is classified as a type 5 phosphodiesterase inhibitor, which is an enzyme responsible for correct circulation in reproductive organs. Sildenafil works well for neurological and mental erectile dysfunction. The drug does not work in case of low blood pressure or even cavernous atrophy.
Sildenafil - action
The action of the sildenafil substance is based on the relaxation of smooth muscles in cavernous bodies. This allows for an efficient blood flow to the penis, which results in the achievement of an erection. The component called guanosine monophosphate in this process is broken down in cavernous bodies. This leads to the activity of the compound - phosphodiesterase type 5. Since sildenafil only acts in the final stage of the whole chemical process, it does not cause an automatic erection, but still requires sexual stimulation. In people with pulmonary hypertension, pulmonary vasodilators with slight vasodilation in the general circulation may be enlarged.
Despite its high effectiveness, safety and low probability of side effects, Sildenafil may cause undesired effects. The most common are headaches and dizziness, muscular pains, hot sensation in the facial area, temporary visual disturbances, nausea or indigestion.
Sildenafil - contraindications
The drug should not be used in case of ischemic heart diseases, uncontrolled arterial pressure, malignant hypertension, malignant ventricular arrhythmia, cardiomyopathy, liver and kidney failure. Sildenafil should not be used if you are allergic to the main component of the drug. It is not recommended that people who have just had a heart attack, stroke or myocardial infarction should not take the chemical compound.
Sildenafil - indications
Sildenafil is indicated for use by men who want to achieve satisfaction with having sexual intercourse. A proper erection is possible at the moment of sexual stimulation. The drug should be taken 6 hours before the planned intercourse. The preparation may not be effective in case of people with erection problems resulting from cavernous atrophy or low blood pressure.